This information is for US healthcare professionals only.
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To help you and your doctor add Myalept to your current generalized lipodystrophy (GL) treatment plan, the Amryt Assist team is built around you.
Amryt Assist helps provide the support services and resources you need when you need them. When you sign up for the Amryt Assist Program, you can access these support services at no cost to you.
A dedicated Amryt Clinical Educator is ready to help with these services:
An Amryt Clinical Educator can provide one-on-one education about GL and Myalept either in-person or virtually. They are here to support you for the duration of your treatment and can help you stay on track.
A nutrition program was developed to help you and your doctor create a healthy eating plan specifically for GL. Your Amryt Clinical Educator is here to assist you along your journey.
Myalept is available only through Specialty Pharmacies. Your Specialty Pharmacy will fill your prescription each month and deliver it directly to you whether you are at home or at work or even if you are traveling or moving. The Specialty Pharmacy provides information on possible interactions with any other medications you may be taking, so be sure to tell the pharmacist and your doctor about all your medications, including vitamins and herbal supplements. Also, the Specialty Pharmacy can help you stay on track with Myalept treatment by calling to remind you about refills.
Your dedicated Amryt Assist Nurse Case Manager works to make the insurance process easier for you. He or she can help you understand the cost of treatment and refer you to independent financial assistance programs.
As you prepare to begin treatment, an Amryt Assist registered nurse is available to provide in-person injection training at your home or doctor’s office—at no cost to you—on how to mix and inject Myalept and administer your medication.
What is Myalept?
Myalept® (metreleptin) is a leptin replacement therapy used with a doctor-recommended diet to treat problems caused by not having enough leptin (leptin deficiency) in people with generalized lipodystrophy.
Important Safety Information
Myalept is only available through a restricted program called the Myalept Risk Evaluation and Mitigation Strategy (REMS) Program. Your doctor must be enrolled and certified in the program in order to prescribe Myalept.
Myalept may cause serious side effects, including:
You should not take Myalept if you:
Before using Myalept, tell your doctor if you have any medical conditions including if you:
Other possible side effects
The most common side effects of Myalept include headache, low blood sugar, decreased weight, and/or abdominal pain.
You may get low blood sugar (hypoglycemia) if you take Myalept with other medicines used to lower blood sugar, such as insulin or sulfonylurea. Your doses of these medications may need to be lowered while you use Myalept. Tell your doctor right away if you experience shakiness, sweating, headache, drowsiness, weakness, dizziness, confusion, irritability, hunger, fast heartbeat, or a jittery feeling because these may be signs of low blood sugar (hypoglycemia).
For newborns and infants, mix Myalept with sterile water for injection (preservative-free) (WFI). Serious side effects including death have happened in newborns or infants who have received the preservative benzyl alcohol. Bacteriostatic water for injection contains benzyl alcohol and it should not be used to mix Myalept for newborns and infants.
Myalept may worsen symptoms caused by certain problems in your immune system (autoimmune disorder). Ask your doctor about what symptoms you should watch for that may require further testing.
Talk to your doctor about any side effect that bothers you or that does not go away. These are not all the possible side effects of Myalept. For more information, speak to your doctor or pharmacist. Tell your doctor about all the medications you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. Take Myalept exactly as your doctor instructs you.